Stop the new gene, the alien: Breakdown of transgenes and introgressions by ncRNA mediated gene regulations

Abstract

Acclimatization is a process that occurs in individual cells to a drastic change in micro and macro environments. When an organism is subjected to a new environment or a change in its normal growing conditions, the cellular mechanisms initiate a warning sign and over a period of time or over generations the acquired, modified traits are being communicated and fixed as a new trait. If there is no balance with in the cell due to over expression of a single gene or set of associated genes either manmade or due to mutations, the organism or plant tries to fix it by initiating a set of gene regulation mechanisms. According to our neutral theory of gene expression, always a cell tries to maintain its pH by modifying its cytosol through altered gene expression. If this gene expression is modified to an extent where it may not be able to fix it, or it needs to fix the trait by excessive energy loss then the organism initiates its gene regulation leading to breakdown of the introduced trait over few generations.